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The study was conducted to identify whether CBD lowers the blood pressure in humans or not. It was indicated that the non-psychoactive agent CBD helps in reducing the blood pressure after a single dose. Exploring Effects Of Cannabinoids On Blood Pressure – CBD Hemp Exploring Effects Of Cannabinoids On Blood Pressure August 8, 2016 Written by HempOilFacts.com Cannabinoids (including CBD, CBC, THC and many others) have individualistic effects on the human body along with a collective effect (termed the Entourage Effect). Drugs That May Interact with CBD Oil | Learn More | CBD Oil CBD oil interacts with the endocannabinoid system in a way that produces very few unintended side-effects. While the majority of the vast majority of the science indicates CBD oil is safe for use and consumption, it does pose a few risks that, if not properly understood, could be dangerous.